CoQ10 (coenzyme Q10) supplements come in two forms: ubiquinone, the oxidised form used in most supplements and most research, and ubiquinol, the reduced form, which is more expensive and less stable. The body converts between the two. Supplements usually provide 30–300mg a day; CoQ10 is fat-soluble, so it is best taken with a meal containing some fat. There are no authorised health claims for CoQ10 in the UK, and anyone taking blood-thinning medicine such as warfarin should check with their GP first.
1. What CoQ10 is
Coenzyme Q10 is a fat-soluble compound made by the body and found in every cell, with the highest amounts in organs such as the heart, liver and kidneys. Small amounts come from food, mainly meat, oily fish, offal, nuts and some oils. Supplements are made by fermentation (using yeast or bacteria) or by chemical synthesis.
2. Ubiquinone vs ubiquinol at a glance
| Ubiquinone | Ubiquinol | |
|---|---|---|
| Form | Oxidised CoQ10 | Reduced CoQ10 |
| In supplements | The most common form | Less common |
| Stability | Stable in capsules and powder | Oxidises easily; usually sold in softgels |
| Research | Used in most published studies | Fewer studies |
| Price | Lower | Typically several times higher per mg |
| In the body | The body converts between the two forms as needed | |
3. How much CoQ10 is in a supplement?
Strengths on UK shelves range from about 30mg to 300mg per capsule. A low-strength product can mean taking several capsules a day to reach a commonly used amount, so compare the mg per capsule and the cost per 100mg, not just the price per pot.
4. What to check on the label
- Form: ubiquinone or ubiquinol, stated clearly.
- Amount per capsule and how many capsules make one serving.
- Source: fermented CoQ10 is the trans-isomer, the same form the body makes.
- Fillers: look for a short ingredient list without bulking agents.
- Diet: capsule shell (gelatine or vegetable), and allergens.
5. How to take CoQ10
Because CoQ10 is fat-soluble, take it with a meal that contains some fat. One capsule a day with breakfast or lunch is a simple routine.
6. Who should check with a doctor first
CoQ10 may interact with some medicines, particularly blood thinners such as warfarin, and with some blood-pressure and diabetes medicines. Speak to your GP or pharmacist first if you take any medication, or if you are pregnant or breastfeeding.
7. JeaKen CoQ10
| Product | Form | Per capsule | Pack | Price |
|---|---|---|---|---|
| Coenzyme Q10 200mg | Ubiquinone, naturally fermented | 200mg | 120 capsules (4 months at one a day); vegan | £28.95 (about 24p a day) |
Price correct at the time of writing; see the product page for the current price.
Frequently asked questions
What is the difference between ubiquinone and ubiquinol?
Ubiquinone is the oxidised form of CoQ10 and ubiquinol the reduced form. The body converts between them. Ubiquinone is the most common and most studied supplement form; ubiquinol costs more and is less stable.
How much CoQ10 should I take?
Supplements commonly provide 30–300mg a day. Follow the directions on the label; JeaKen CoQ10 is one 200mg capsule a day.
When is the best time to take CoQ10?
With a meal containing some fat, because CoQ10 is fat-soluble.
Can I take CoQ10 with warfarin or other medicines?
CoQ10 may interact with blood thinners such as warfarin and some other medicines. Speak to your GP or pharmacist before taking it.
Is CoQ10 vegan?
It can be. Fermented CoQ10 in a vegetable capsule is suitable for vegans; check the capsule shell on the label.
Are there health claims for CoQ10?
No health claims for CoQ10 are authorised in the UK. Food supplements should not be used as a substitute for a varied and balanced diet.
Food supplements should not be used as a substitute for a varied and balanced diet. If you take any medication, are pregnant or breastfeeding, speak to your GP or pharmacist before starting a supplement.
Sources
- NCCIH (US National Institutes of Health) — Coenzyme Q10 fact sheet, including medicine interactions.
- EFSA — scientific opinions on health claims for coenzyme Q10 (cause-and-effect not established).
- GB Nutrition and Health Claims Register — authorised claims for food supplements in Great Britain.
